Author's response to reviews Title:Chromosomal alterations in exfoliated urothelial cells from bladder cancer cases and healthy men: a prospective screening study Authors:
نویسندگان
چکیده
Nadine Bonberg ([email protected]) Beate Pesch ([email protected]) Thomas Behrens ([email protected]) Georg Johnen ([email protected]) Dirk Taeger ([email protected]) Katarzyna Gawrych ([email protected]) Christian Schwentner ([email protected]) Harald Wellhäußer ([email protected]) Matthias Kluckert ([email protected]) Gabriele Leng ([email protected]) Michael Nasterlack ([email protected]) Christoph Oberlinner ([email protected]) Arnulf Stenzl ([email protected]) Thomas Bruening ([email protected])
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N-Acetyltransferase 2 genotype, exfoliated urothelial cells and benzidine exposure.
Most studies report an association of the slow N-acetyltransferase 2 (NAT2) status with elevated bladder cancer risk. In this study, NAT2 genotypes and the decades-long records of Papanicolaou's grading of exfoliated urothelial cells in a former benzidine-exposed cohort of the Shanghai dyestuff industry (29 bladder cancer patients; 307 non-cancer cohort members, some of them presenting differen...
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Micropapillary variant of urothelial carcinoma (UC) of the bladder is an aggressive tumour, comprising 0.6-6% of all UC. It generally presents with high-grade and stage, and has been reported as having a worse prognosis when compared to traditional UC. We report the case of a 58-year-old man who presented with macroscopic haematuria. The patient was diagnosed with high-grade urothelial carcinom...
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Objective- The current study was conducted to evaluate changes in the urinary bladder structure and leukocyte profile as an important index of the systemic inflammation response for two different types of spinal cord injury (SCI) in a rat model. Design- Experimental Study.Animals- Forty adult healthy female Sprague-Dawley rats.<br /...
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Effect of intravesical Bacillus Calmette-Guérin on detection of a urothelial differentiation antigen in exfoliated cells of carcinoma in situ of the human urinary bladder.
Flow cytometry was used to detect and quantify expression of a urothelial differentiation antigen (Om5) and nuclear DNA in exfoliated epithelial cells of the urinary bladder from 15 patients with nonpapillary carcinoma in situ during and after intravesical therapy with Bacillus Calmette-Guérin (BCG). Before BCG treatment exfoliated cells reacting with the mouse monoclonal antibody Om5 were foun...
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